Circular Dichroism beyond single-point checks: First accredited ISO 17025 CRMs deliver spectrum-wide confidence

Circular Dichroism (CD) spectroscopy is central to structural biology and chiral analysis. However, in 2025, many laboratories still rely on camphor-10-sulfonic acid (CSA) or ammonium camphorsulfonate (ACS) for instrument verification. These traditional methods require fresh preparation, are prone to hygroscopic error, and only validate a single peak near 290 nm. The result: The visible range goes untested, and compliance is left exposed.

Starna leads the industry with its Certified Reference Materials (CRMs) for CD. Each set contains permanently flame-sealed quartz cells – Blank, R,R, and S,S enantiomers – spanning both UV and visible regions (190–700 nm and 400–700 nm). Ready-to-use, these references eliminate weighing and waiting, removing preparation variability and ensuring reproducibility across instruments and locations.

Certification extends beyond static tables. Every set features a continuous Δε(λ) model and U95 uncertainty envelopes, so users can verify performance at any wavelength with confidence. For those who prefer a rapid check, certificates highlight key maxima and minima: anchor points at 210, 237, 274, and 545 nm for UV, and 446, 479, 545, and 605 nm for VIS. Spot-checking instrument performance becomes straightforward, with no need for complex calculations. Certificates are valid for two years, offering lasting assurance between renewals.

As the first and only producer with an accredited (UKAS) scope for CD CRMs, Starna combines ISO 17034 production and ISO/IEC 17025 calibration for unmatched traceability and compliance. This achievement ensures every set is certified with globally recognised traceability for audit-ready documentation and spectrum-wide reliability.

For regulated environments, the advantages are clear: objective acceptance criteria, reduced operational risk, and data integrity you can defend. Say goodbye to stresses that result from last-minute scrambling to prepare unstable CSA solutions, or worrying about gaps in instrument calibration. With Starna UKAS-accredited CD spectroscopy standards, you can demonstrate compliance and reproducibility across the full spectrum.

Ready to move beyond single-point checks? Request a certificate sample or technical briefing today to experience how Starna Certified Reference Materials can transform your laboratory’s approach to CD instrument qualification.

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