Unlocking Molecular Mirrors: Exploring the World of Chiral Chromatography Labmate Online

Chiral

Kromasil silica-based materials have a solid history in the biotechnology, pharmaceutical and natural product fields, because of the benefits these stationar...

First in class stationary phases for chromatographers

Chromatography

We are pleased to celebrate the 30 years of Kromasil, the high performance chromatographic media based on state-of-the-art silica for industrial HPLC, SFC an...

Kromasil’s 30 years of continuous collaboration with chromatographers

Chiral

The Genevac Rocket™ Synergy Evaporator is a powerful tool proven to accelerate traditionally difficult and time consuming chiral separation protocols. I...

Flexible Evaporator Enhances Chiral Separation

Chromatography

From a Trump presidency to the Brexit vote, 2016 was full of surprises to say the least. So what’s in store for 2017? While politics is fascinating, the ni...

What Space Events Does 2017 Have in Store?

Chiral

Polarimeters measure the rotation of plane polarised light as it passes through a solution containing an optically active component such as a sugar (sucrose,...

Polarimeter Series Provides High Sensitivity Readings of Pharmaceuticals...

Chiral

Chiral Technologies, Inc., part of Daicel Corporation and a leader in enantioselective chromatography, are to sell Daicel’s chiral reagents in the U.S. and...

Strem Chemicals to Channel Chiral Products into Europe

Chiral

ACQUITY UPC2 System and Columns Using inexpensive and non-toxic compressed liquid CO2 as a primary mobile phase, the ACQUITY UPC2® System gives scientist...

ACQUITY UPC2 System and Columns

Chiral

ES Industries is launching ChromegaChiral CCC™ a new product for high resolution chiral separations and purification by super critical fluid chromatography...

Product for high resolution SFC or HPLC Chiral Separations Launched

Chiral

Chiral Technologies Worldwide has announced the availability of i-CHIRAL 6, a set of six Daicel 3-µm immobilised CSPs packed in columns of 4.6 mm internal d...

New Advanced Screening Set Announced

Chiral

Goal To demonstrate the simultaneous enantiomeric separation of beta blockers using UltraPerformance Convergence Chromatography™, resulting in time and...

Simultaneous Enantiomeric Separation of Multiple Beta Blockers Using Ult...

What is Chiral chromatography?
Chiral chromatography is a separation technique used to separate and analyze chiral compounds, which are molecules that exist in two non-superimposable mirror image forms called enantiomers. These enantiomers have identical physical and chemical properties but exhibit different interactions with other chiral molecules, such as those found in biological systems.

In chiral chromatography, the stationary phase is typically a chiral compound or a chiral selector that interacts selectively with one enantiomer over the other. This interaction causes the enantiomers to elute from the chromatographic column at different rates, leading to their separation. Common types of chiral chromatography include normal-phase chiral chromatography, reversed-phase chiral chromatography, and supercritical fluid chromatography.

Chiral chromatography is widely used in various fields such as pharmaceuticals, agrochemicals, food chemistry, and environmental analysis to analyze and separate chiral compounds for research, quality control, and regulatory purposes. It plays a crucial role in drug development and manufacturing, where the separation of enantiomers is essential to ensure the efficacy and safety of pharmaceutical products.