Triple quadrupole MS accelerates high-throughput analysis

A next-generation triple quadrupole mass spectrometer from Thermo Fisher Scientific, designed for busy, results-driven laboratories, has been launched, offering major gains in speed, robustness and day-to-day reliability across biopharma, clinical translational research, environmental monitoring and food safety testing.

The TSQ Certis™ triple quadrupole mass spectrometer introduces a hardware and software package aimed squarely at one of the biggest demands in routine quantitative workflows: keeping instruments running for longer, with minimal downtime, while still generating confident, reproducible data.

Engineered for sustained, uninterrupted throughput, the system has been stress-tested to withstand more than 10,000 injections without cleaning, helping laboratories maintain productivity over long analytical runs. This ruggedness is combined with enhanced ionisation performance through an upgraded OptaMax™ Plus ion source, allowing sensitive detection of trace-level contaminants and accurate quantification of demanding analytes, including complex therapeutic peptides such as GLP-1 analogues.

For laboratories handling rising sample numbers, the TSQ Certis MS also delivers significant speed improvements. The instrument can acquire over 900 SRM transitions per second, supporting large targeted quantitation panels without compromising data quality. Built-in predictive monitoring tools provide early notice of service needs, helping labs avoid unexpected interruptions.

Ease of use has been emphasised throughout the platform. Method templates and guided workflows mean both new and experienced users can achieve consistent results quickly, while direct integration with Chromeleon™ Chromatography Data System ensures secure, compliant data handling and enterprise-scale instrument management.

Pushkin Pant, Vice President and General Manager of Life Sciences Mass Spectrometry, Chromatography and Mass Spectrometry at Thermo Fisher Scientific, said the system was designed to help routine laboratories work with greater confidence. “The TSQ Certis MS supports analytical scientists tackling challenges such as detecting trace contaminants in food or measuring increasingly complex biotherapeutics,” he said. “By combining robust hardware, predictive maintenance and compliance-ready software, we’re aiming to help labs focus their time where it matters most.”

The TSQ Certis MS is aimed at analytical scientists and lab managers across biopharmaceutical development, clinical and translational research, environmental testing and food safety, where reliable uptime, consistent quantitation and scalable data compliance are essential.

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