iBox® Scientia™ In Vivo Imaging System for Fluorescent and Bioluminescent applications

The iBox Scientia features high sensitivity imaging and accurate quantification of bioluminescent and fluorescent sources. The new BioCam 900 camera provides superior imaging capabilities for bioluminescence. It has a deeply cooled CCD (-100ºC from ambient), superior quantum efficiency (>90%) and a selection of low f-stop (f/0.95) lenses for ultra-fast capture.

The system is versatile and can support imaging of any probe in the visible to near infrared (NIR) range. NIR enables less skin autofluorescence (~650nm) and deep penetration with use of RFP for (3X) 2 penetration depth and GFP, NIR for near (8X) 2 penetration depth. The wide spectrum also allows more options for multiplex labelling. This capability displays tissue/tissue interaction, enhanced signal to background ratio and detection of multiple fluorescent proteins or labels.

Applications for pre-clinical research include tumour studies, cancer research, inflammation, heart disease, immunology, bacterial/viral infections, metastasis and gene expression.

For full Application Notes on these topics, please visit www.uvp.com.