Collaboration on Research Project for Huntington’s Disease Announced

Proteome Sciences plc has announced that they will collaborate with CHDI Foundation, Inc on a systems biology project regarding Huntington’s disease. Initially, Proteome will provide its PS Biomarker Services™ protein profiling to CHDI’s research programs. The analyses will be performed at Proteome’s facility in Frankfurt am Main, which is certified according to the international quality standards of ISO 9001:2008.

Commenting on the collaboration, Dr Ian Pike, COO at Proteome, said “We are delighted that CHDI has selected PS Biomarker Services™ to deliver potential proteomic markers that could help elucidate mechanisms of Huntington’s disease pathology. The link between the Huntington’s disease genotype and disease phenotype remains poorly understood and we will apply our Tandem Mass Tag workflows to provide high density protein expression maps in cell lines carrying different CAG-repeat lengths. Proteome Sciences has previously performed studies to identify biomarkers of HD progression in blood, and several of these are being independently evaluated as potential pharmacodynamic markers in the PADDINGTON study.”

Jamshid Arjomand, PhD, Director, Basic Research at CHDI, said “We are excited to implement a robust proteomic platform in support of our systems biology efforts at CHDI. Proteome Sciences’ expertise in this domain will provide an additional layer of information to help us and the wider HD research community probe the pathological mechanisms involved in this devastating disorder.”