• Project to tackle scalability during cell therapy manufacture
    Matthew Durdy

News & Views

Project to tackle scalability during cell therapy manufacture

Jun 19 2024

A collaboration between The Cell and Gene Therapy Catapult (CGT Catapult) and Plurify, a recent spinout from the CGT Catapult and Deep Science Ventures has received over £340,000 funding from Innovate UK as part of the Transforming Medicines Manufacturing Programme. The project will focus on technology development that will improves the purity of cell therapies, to make them safer, more efficacious and less costly to produce.

During production of cell therapies, unwanted cell types can form in the product which can impact the effectiveness of the treatment or, in the worst cases, can cause the patient harm. Existing approaches to remove these impurities are not fully effective or scalable, presenting a barrier to both the development and use of these therapies.

The funding will enable the partnership to develop and test a technology that removes the unwanted residual cells and work with the cell therapy industry, by applying this technology to individual developers and manufacturers’ own production processes.

Matthew Durdy, Chief Executive of the CGT Catapult commented: “Plurify’s innovative technology and expertise could overcome existing challenges in the development of cell therapies. Through working with this exciting organisation to create a scalable technology that improves the safety and efficacy of these products, we aim to help more therapies progress to market and become available to patients.”

Djordje Djordjevic, Co-Founder and CEO of Plurify commented: “We are very grateful to Innovate UK for awarding us this grant, which is helping us develop and apply our novel purification technology in industrially relevant settings. It’s wonderful that we can simultaneously deepen our collaboration with the CGT Catapult, tapping into their depth of expertise and ensuring our strategic alignment with the realities of UK’s cell and gene therapy industry. We are very excited for the outcomes of this project which will bring a new solution to cell therapy manufacturers to ultimately get more next-generation therapies to the patients that need them.”

More information online


Digital Edition

International Labmate Buyers' Guide 2024/25

June 2024

Buyers' Guide featuring: Product Listings & Manufacturers Directory Chromatography Articles - Enhancing HPLC Field Service with fast-response, non-invasive flowmeters - Digital transformatio...

View all digital editions

Events

EuCheMS Chemistry Congress

Jul 07 2024 Dublin, Ireland

HPLC 2024

Jul 20 2024 Denver, CO, USA

ICMGP 2024

Jul 21 2024 Cape Town, South Africa

ADLM 2024

Jul 28 2024 San Diego, CA USA

InaLab 2024

Jul 30 2024 Jakarta, Indonesia

View all events