University of Dundee Installs Biacore 4000 SPR System

The University of Dundee has become the first facility worldwide to take delivery of a Biacore™ 4000 system which will be used to focus on developing biophysical fragment based screening methodologies for efficient
drug discovery.

Dr Iva Navratilova, Independent Investigator, University of Dundee and founder of spinout Kinetic Discovery, commented: “We are developing biosensor based screening methods that enable us to characterise the kinetics and thermodynamics of molecular interactions. The unprecedented combination of high sample capacity and sensitivity provided by Biacore 4000 means we can now carry out highly accurate screening of our fragment library in only a couple of days, rather than the weeks it would have otherwise taken.”

Dr Navratilova also plans to use Biacore 4000 to continue her work on developing biosensor SPR methods for screening native membrane proteins such as GPCRs, an important class of drug targets.

“We’re very excited to be the first facility to install a Biacore 4000 instrument”, said Professor Andrew Hopkins, Chair of Medicinal Informatics and SULSA Research Professor of Translational Biology, University of Dundee, and CEO of Kinetic Discovery: “We believe this reinforces our position as a world leader in the field of SPR based fragment screening, and we look forward to seeing the many benefits the purchase will make to our research efforts.”