ASTM Publishes E2834 Standard Defining Nanoparticle Tracking Analysis

NanoSight is delighted to welcome publication of American Society of Testing Materials ASTM E2834 - Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA).

This document details application of Nanoparticle Tracking Analysis (NTA) to measurement of particle size distributions for suspended particles from ~10nm to the onset of sedimentation.

Duncan Griffiths, NanoSight's USA West Sales Manager commented: "This document has taken almost three years to develop. It provides a rigorous review of the core science driving Brownian motion and the derived parameters of mean, mode, percentile values and concentration. The scrutiny of demanding third-party experts has been fundamental in producing a thorough appraisal of NTA. The result is a meticulous presentation of science and methodology. We are delighted."

The UK's National Physical Laboratory (NPL) has seen NanoSight develop NTA since its early days more than five years ago. Helen Sharman from NPL commented: "NPL has been working on the characterisation of nanomaterials for many years, in-part collaborating with NanoSight. The nanomaterials team has followed the development of the NTA technique with great interest due to its unique capability in the area of nanometrology. As the UK's national measurement institute, NPL recognises the importance of this standard and the capability of the NanoSight instrumentation to provide consistent, precise and comparable data."

NanoSight CEO Jeremy Warren added: "Whilst this standard is a milestone, it is also a building block. Many NanoSight users have requested this definition of the technique as they present data in research papers and to regulatory bodies for product approvals and clinical trials. We will now move to provide industry with test methods for specific materials to help lock down SOPs. The timing of this publication is helpful as the European Commission move to consider methodologies to address the characterisation challenges of their recently-published definition of nanomaterials. Here we see a significant role for NTA's unique nanoparticle counting capability".

The Standard is available from ASTM at www.astm.org/Standards/E2834.htm