Elevate Your Research with Sigma-Aldrich's Anhydrous Solvents and Sure/Seal^TM Packaging System

In chemical synthesis and pilot-plant laboratories, the integrity of reagents is crucial, especially for moisture-sensitive reactions. Sigma-Aldrich, a brand under Merck KGaA, Darmstadt, Germany, offers the highest quality anhydrous solvents and an innovative Sure/Seal™ packaging system that ensures reagent stability and purity.

The Largest Portfolio of Anhydrous Solvents

Sigma-Aldrich provides an extensive range of over 100 high-quality anhydrous solvents, maintaining exceptionally low water content. This portfolio includes commonly used solvents like Hexane, Toluene, and Tetrahydrofuran, as well as greener solvent alternatives for DMF and NMP such as γ-Valerolactone (GVL) and Dimethyl isosorbide (DMI). Available in sizes from 100 mL to 2 L, these solvents meet diverse research needs.

The Sure/Seal™ Packaging System: A Scientific Innovation

The Sure/Seal™ packaging system exemplifies Sigma-Aldrich's dedication to quality and innovation. This air-tight system protects product quality even after multiple septum punctures. It features three unique plug-style liners, each designed for optimal compatibility with different solvents. For instance, the white liner is suitable for Hexane, Toluene, and Dichloromethane, while the gray liner is ideal for 1,4-Dioxane, Methanol, and Acetonitrile.

Scientific studies highlight the Sure/Seal™ system's superior ability to prevent moisture uptake. During a five-week test period, the Sure/Seal™ system demonstrated an average weekly moisture gain of only ~8.3 ppm for Methanol, compared to ~86.2 ppm for a leading competitor. This ensures that the solvent's integrity is maintained throughout its shelf life.

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Key Benefits for Researchers

For researchers, the exceptionally low water content of Sigma-Aldrich's anhydrous solvents ensures that moisture-sensitive reactions proceed without interference, leading to more accurate and reproducible results. The Sure/Seal™ packaging system provides confidence that the solvent's integrity is preserved even after multiple uses, reducing the frequency of solvent replacement, and minimizing contamination risks.

Sigma-Aldrich's anhydrous solvents and Sure/Seal™ packaging system set the standard for quality and innovation in chemical synthesis. Explore the full, now extended range of anhydrous solvents.