Next-Generation Fluorescent In Situ Hybridisation Assays for Molecular Analysis

Agilent Technologies Inc have introduced Agilent SureFISH probes, the next generation of fluorescent in situ hybridisation (FISH) assays, delivering a comprehensive menu of the industry’s highest resolution probes for a wide range of molecular analysis applications.

Agilent SureFISH probes deliver dramatically better performance compared to existing FISH products. SureFISH probes enable users to specifically detect aberrations in regions of the genome as small as 50kb, as well as aberrations near highly repetitive regions. They provide higher resolution and faster hybridisation times than  competing technologies and are designed to enable users to meet American College of Medical Genetics guidelines for clinical cytogenetics.

Manufactured at Agilent’s Cedar Creek, Texas, facility, which is registered with the US Food and Drug Administration as a medical device establishment, Agilent SureFISH probes are Class I Analyte Specific Reagents. They are manufactured under Quality Standard Regulations and current Good Manufacturing Practices.

“We’re making a major impact in the cytogenetics  community with a comprehensive portfolio of highperformance

products that enable cytogenetic researchers to choose a molecular analysis method that best fits their needs,” said Robert Schueren, Agilent Vice President and General Manager, Genomics. “Our comprehensive cytogenetics portfolio includes SureFISH probes, CGH and CGH+SNP arrays, scanner and Agilent CytoGenomics software. Customers now have a single source for all their cytogenetics needs.”

Agilent offers an extensive menu of FISH probes for constitutional and cancer applications. The initial menu includes hundreds of SureFISH probes for the most common regions, to accommodate a wide range of cytogenomic research needs. Agilent plans to introduce additional SureFISH probes later this year. Customers can easily select SureFISH probes at the new SureFISH website www.agilent.com/genomics/SureFISH. The SureFISH chromosome browser facilitates probe selection and online purchase. The site also includes images of all probes hybridised at four and 14 hours, allowing users to see the probe performance prior to purchase.