Chromatography
Infographics: Inert vs Conventional UHPLC Analysis of Biomedicals
Jul 16 2025
In the realm of biomedical analysis, the choice of Ultra-High Performance Liquid Chromatography (UHPLC) systems can significantly impact the quality and reliability of results. Traditional stainless steel-based UHPLC systems often face challenges such as adsorption of biomolecules to metal surfaces, leading to reduced sensitivity, lower reproducibility, peak tailing, and sample loss. These issues can compromise the accuracy and efficiency of biomolecule analysis.
In contrast, the Nexera XS inert UHPLC system offers a bioinert and biocompatible solution that addresses these common problems. By utilising a metal-free sample flow path, the Nexera XS inert prevents unwanted interactions with biopolymers, ensuring no sample loss and excellent separation. This innovative approach enhances sample recovery, increases sensitivity, improves resolution, and elevates overall efficiency.
The Shimadzu Nexera XS inert system is designed to provide high-quality and reliable data, making it particularly well-suited for the analysis of biopolymers such as antibodies, peptides, and nucleic acid drugs. With its advanced features and corrosion-resistant materials, the Nexera XS inert UHPLC system sets a new standard in biomolecule analysis.
Would you like to find out more about the differences between inert and conventional UHPLC systems? Download the infographics here to explore the benefits and innovations of the Nexera XS inert UHPLC.
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