MOU for Analyses of Biologics and Vaccines

Agilent Technologies Inc, the Glyco-MEV laboratory at the University of Rouen, in France, and the Bioprocessing Technology Institute (BTI) at the Agency for Science, Technology and Research (A*STAR), in Singapore, have signed a memorandum of understanding to work together in order to develop tools to effectively analyse biologics and vaccines.

Biologics are molecules such as antibodies and other recombinant protein-based therapeutics. Used in combination with vaccines, they can prevent or treat a variety of serious medical conditions such as cancers, immune disorders and infectious diseases that affect millions of people annually. These therapeutic agents are typically produced by bioprocesses using living cells as factories for their production.

BTI is currently working to develop methods of producing and analysing these biologics in animal cells while Glyco-MEV laboratory specializes in the production of those molecules in plant systems.

This strategic partnership strengthens the collaboration between BTI and Glyco-MEV laboratory and is enhanced by Agilent’s technological expertise to develop new, sensitive and high-throughput methodologies that are particularly adapted to the analysis of biopharmaceuticals. In addition, the Glyco-MEV laboratory will be Agilent’s glycomics reference site in Europe, and BTI will be its glycomics reference site for Southeast Asia.

Professor Lam Kong Peng, executive director of BTI, said, “With increasing use of biologics to treat human diseases and with more biosimilars coming to market in the next few years, it is timely for BTI to develop novel technologies that would improve the characterization and analysis of protein-based drugs. This collaboration would enhance Singapore’s reputation as a world-class destination for biologics manufacturing and R&D.”

“This collaboration will enhance our international expertise with regards to the glycan analysis and engineering of biopharmaceuticals produced in plant and microalgae cells,” said Prof Patrice Lerouge, director of the Glyco-MEV laboratory. “We also hope that such a research initiative will facilitate exchanges of lab members and PhD students between Singapore and France.”