Microscopy & Microtechniques
New High Shear Microplate Extends Cellular Pathology Studies
Mar 29 2010
Fluxon Biosciences has introduced a new microplate for its BioFlux live cell imaging workstations, extending their shear flow limits to simulate a variety of pathological vascular conditions. With the new High Shear Plate, the BioFlux systems can be an effective tool in thrombosis and platelet studies, cardiovascular and immunological drug screening and cell/bacteria adhesion research.
The BioFlux 200 and 1000 platforms incorporate Fluxion’s unique Well Plate Microfluidic technology to enable plate-based live cell imaging under shear flow conditions that mimic those in the human body. The BioFlux controller drives the flow of reagents and cells through microfluidic channels running between the wells. Fully programmable changes to shear flow can be made in real time.
The standard BioFlux 48-well plate is suited for studying normal flow conditions in the body, while the new High Shear Plate enables assays under the increased flow characteristic of diseased vasculature. The new High Shear Plate is compatible with both the BioFlux 200 and the higher throughput, fully integrated BioFlux 1000 system. The presterlized SBS-standard 48-well plates can be used for up to 24 simultaneous flow experiments.
“In the presence of cardiovascular disease, where blood vessels can narrow considerably, shear stress is amplified,” explained Michael Schwartz, Product Manager for Fluxion. “Because shear stress levels affect platelet and endothelial cell morphology and receptor expression, creating flow conditions for cellular assays is an important advantage.”
Digital Edition
International Labmate Buyers' Guide 2024/25
June 2024
Buyers' Guide featuring: Product Listings & Manufacturers Directory Chromatography Articles - Enhancing HPLC Field Service with fast-response, non-invasive flowmeters - Digital transformatio...
View all digital editions
Events
Jul 03 2024 Gandhinagar, India
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa
Jul 28 2024 San Diego, CA USA