Proteomics Analysis Software Updated

Thermo Fisher Scientific Inc have introduced Thermo Scientific Proteome Discoverer software version 2.0 for analysing qualitative and quantitative proteomics data. As part of the release, the company announced a non-exclusive agreement with Protein Metrics, Inc to license the company’s Byonic™ database search software, adding next-generation capability to streamline analysis of glycopeptides and other post translational modification data.

Proteome Discoverer software version 2.0 combines spectral library searching with classical database searching for fast, highly reliable identification of true positive peptide spectrum matches. The software also includes a multi-threaded SEQUEST® search engine that takes advantage of the latest computer architecture to accelerate database searches. The software’s peptide and protein false discovery rate and probability (PFDRP) feature provides high-confidence identification of proteins and peptides. High-confidence measurement of phosphorylation sites is provided by PhosphoRS 2.0, included in Proteome Discoverer 2.0.

The new version of Proteome Discoverer software also generates reports automatically, saving users large amounts of time and effort. This is especially useful for large studies where hundreds of files are interpreted.

Proteome Discoverer software version 2.0 is compatible with all current Thermo Scientific Orbitrap-based LC/MS instruments. Planned shipping date is December 1, 2012.

Protein Metrics’ PreviewTM software is also now available through Thermo Fisher. Preview software samples MS/MS data to measure mass errors, digestion specificity and modifications for subsequent full protein database search.