• Mini Bioreactor System accelerates Process Scale-up of Biological Therapies and Vaccines

Laboratory Products

Mini Bioreactor System accelerates Process Scale-up of Biological Therapies and Vaccines

Jun 22 2014

TAP Biosystems have announced that its new ambr250™ automated mini bioreactor system has already been chosen by a number of major pharmaceutical, biotech and CRO firms as a high-throughput, scale-down bioreactor model for their process development and optimisation programmes.

The automated ambr250 system, which has independent parallel control of 12 or 24, single-use 250 mL bioreactors, is being sited at the R&D centres of the top Pharma companies across the US and Europe. The system has also been chosen for the Chinese R & D centre of a major European biopharm; a major CRO in the UK and a UK-based biotech company.  The majority of these systems will be used to accelerate mammalian and microbial process development and optimisation of antibody and other protein-based therapeutics. However, three of the systems will be utilised in rapidly developing process optimisation for the production of vaccines.

The companies have chosen the ambr 250 because the high-throughput system has the flexibility to culture mammalian lines including CHO or microbial cells such as Pichia pastoris and E.coli  in single-use, stirred bioreactors and utilises continuous pumped feeds, making it possible to fully evaluate the process characteristics of large scale bioreactors and fermenters.

Mwai Ngibuini, ambr250 Product Manager at TAP Biosystems said: “The bioprocessing industry is looking for a realistic scale-down model to accelerate process development and optimise scale-up of cell culture manufacturing processes. The ambr250 system has been rigorously tested by the top pharma firms and it is our expectation that it will be widely adopted across the industry.”

Ngibuini added: “These pharma as well as, CRO and biotech firm installations demonstrate that ambr250 is well-validated, and has universal appeal as an efficient, high-throughput method of scalable process development for a range of industrial cell culture and fermentation applications.”


Digital Edition

LMUK 49.7 Nov 2024

November 2024

News - Research & Events News   - News & Views Articles - They’re burning the labs... Spotlight Features - Incubators, Freezers & Cooling Equipment - Pumps, Valves & Liquid Hand...

View all digital editions

Events

MEDICA 2024

Nov 11 2024 Dusseldorf, Germany

FILTECH

Nov 12 2024 Cologne, Germany

Intech

Nov 12 2024 Tel Aviv, Israel

analytica China

Nov 18 2024 Shanghai, China

Pharma Asia

Nov 20 2024 Karachi, Pakistan

View all events