New Transfection Reagent for Bioproduction Launched

Polyplus-transfection SA have announced the launch of FectoPROTM, the latest optimised transfection reagent in their product portfolio. FectoPRO has been designed for high yields in medium and large-scale production of proteins and antibodies in mammalian cells.

Polyplus has designed FectoPRO to deliver very high protein yields in CHO and HEK cell line systems, the current industry standard systems and most commonly used by bio-production scientists. FectoPRO will also produce up to three times more protein using half the DNA required by other leading commercial transfection reagents. In addition, scientists working with transient gene expression (TGE) systems using FectoPRO will be able to benefit from reproducibility experiment-to-experiment and between reagent batches.

“The bio-production markets, specifically those using larger scale transient transfection systems, have continued to increase their need for higher protein yields whilst decreasing costs and reducing the time to develop viable lead molecules. In our communication with customers, across all sections of this market, these were the consistent and clear messages coming back to us time and time again,” said Mark Bloomfield, CEO of Polyplus-transfection.

“In our hands, FectoPRO gives the highest protein production yields we have ever reached using transient transfection,” said Philippe Funfrock, CEO at ProteoGenix SAS. “Our company offers custom services including protein production in mammalian cells. Being able to produce a lot more protein without revisiting our expression system opens a whole new range of possibilities for our antibody and protein production services.”

The FectoPRO transfection reagent offers scientists working in pharmaceuticals and biotechnology specific advantages over other commercial transfection reagent offerings for bio-production. The reagent is well characterised in terms of chemical structure and is supplied ready-to-use. FectoPRO is also manufactured and formulated using a highly specific and controlled production process in Polyplus’ dedicated manufacturing facility.