New UHPLC Unsurpassed in High-Speed and Productivity

Shimadzu has introduced the Nexera ultra high-performance liquid chromatography (UHPLC) system. The LC-30A Nexera delivers high-speed and high-resolution analysis without sacrificing basic performance
parameters such as excellent precision, near-zero carryover, good linearity, stability and ruggedness. Offering these attributes enables Nexera to provide superior performance in various fields, covering highresolution
and high-speed separation, as well as high-sensitivity detection. Shimadzu’s Nexera is optimised to enable analysis at pressures up to 130 MPa at 3mL/min. This allows for Fast Chromatography as well as highest resolution using long columns with small particles. Without compromising performance and data quality, the maximised pressure over a wide flow range enables various types of analyses, including micro LC to conventional LC, regular pressure LC to ultra high-pressure LC, and isocratic LC to multi-dimensional LC. The system is also suitable for MS applications.

The CBM-20A control unit contains a modified software in order to control the new modules and functionalities. A new micro-reactor based mixer, fully developed components, best materials and technologies and new columns are important from the hardware side driving the performance. The users profit from the productivity and efficiency. Nexera’s fast injection — just 10 seconds — enables fast chromatography to shorten cycle time and result in true high throughput with 4,600+ sample capacity. The newly designed injection port and fine-tipped needle, along with additional features such as three-rinse solvent selection and injection port and internal needle rinse, reduce carryover to an absolute minimum.

For high-temperature LC analysis up to 150°C, Nexera offers efficient pre-heating for solvents to enable stable and reliable conditions. Additionally to the UV and PDA detectors, the brand-new and worldwide most sensitive and fastest RF-20A/20AXS fluorescence detectors can be applied for Nexera.