Streamline your DNA/RNA clean up with PowerClean Pro

The UK release of Mo Bio’s PowerClean Pro DNA and PowerClean Pro RNA cuts the number of steps needed to remove contaminants from DNA/RNA samples while minimising any chance of sample loss. The new clean-up kits, distributed exclusively by Cambio, are the latest in a range of highly effective clean-up kits produced by California-based biotech company, Mo Bio.

Clean-up kits take dirty nucleic acids and remove contaminants that could interfere with downstream processing. Enzyme-dependent applications like restriction digests, ligations, PCR amplification and sequencing all require squeaky clean DNA and RNA in order to get the best (or sometimes any) results.

Cambio already supplies a range of kits from Mo Bio designed to remove proteins, primers, dNTPs and salts often left over after an enzymatic reaction, such as PCR amplification. But if your dirty DNA/RNA sample contains contaminants other than these, you will need to bring out the ‘big guns’.

This is where PowerClean Pro DNA and PowerClean Pro RNA come in. The new PowerClean Pro kits require fewer steps than Mo Bio’s original PowerClean DNA clean-up kit, making it less likely that you’ll lose any sample. The new post-extraction kits contain Mo Bio’s patented Inhibitor Removal Technology (IRT) for removing difficult substances that come from sources like plants, soil, faeces or blood. Common examples of contaminants, along with typical sources, include: humic acids (soil, compost); polysaccharides (plants, undigested contents in the rumen or caecum, faeces, drugs); polyphenols (plants); melanin (hair, skin, eye tissue); bile salts (faeces); haem, EDTA (blood).

If you are trying to remove something not listed here and you are unsure if a PowerClean Pro kit will work, why not try one of the new PowerClean Pro kit samples?