New C18 Cartridges provide High Performance Reversed Phase Flash Purification

Biotage, a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces the launch of Biotage® SNAP ULTRA C18, a range of high performance, reversed phase flash purification cartridges and samplets.

Biotage® SNAP ULTRA C18 reversed phase cartridges are optimised for use with Biotage ACI™ and Isolera™ flash systems and are available in 12 g, 30 g, 60 g, 120 g, 400 g, 950 g and 1850 g cartridge sizes.  They enable chemists to confidently load 2-3% weight percentage of samples onto reversed phase columns, a marked improvement when compared to the currently typical 0.5 - 1% loads. The time taken for purification and solvent usage can therefore be reduced by 50% or a smaller cartridge can be used for the same purification, often with improved purification results.

The new reversed phase cartridges are packed with the new, Biotage® HP-Sphere C18 25 micron spherical silica particles that give a boost to resolution with higher purity peaks over standard reversed phase cartridges.  The silica is chemically neutral with no adverse interactions, ensuring higher yields and better recoveries; a wide diversity of purifications are possible, including the use of both acidic or basic modifiers.

“It is no longer enough for suppliers to arbitrarily work on single aspects of the workflow and purification. Today a more holistic approach is required, one that involves a combination of factors; with this product range we have further augmented the Biotage ACI™ and Isolera™ flash systems and have created a superior product for purification,” said Dr Sunil Rana, Global Product Manager, Biotage.