Biosafety* Features, Workflow Benefits with Avanti Series of High Performance Centrifuges from Beckman Coulter Life Sciences

Energy saving and environmental advantages are key benefits of the Avanti Series of High Performance Centrifuges. They are able to run more quietly, increasing energy efficiency by reducing the air in the chamber, by means of their Friction Reduction System (FRS). This in turn reduces rotor friction, minimising the effort required to accelerate and to maintain speed.

The Friction Reduction System also lowers the amount of heat present in the chamber, reducing refrigeration system usage. For example, the new Avanti JXN-30 can spin at over 100,000 x g while maintaining a 4ºC temperature in the chamber.

The Avanti BioCertified** fixed-angle and swinging-bucket rotors offer a range of biosafety options including a BioCertified dual-locking lid configuration for workflows that include biohazardous samples. This maintains biocontainment when removing and transporting the rotor to a containment hood. Recycled resin is incorporated in the outer panelling of the Avanti centrifuges and each instrument contains up to 3.4kg of recycled PET bottles. 

Extended Rotor Capabilities
Beckman Coulter Life Sciences has capitalised on its unique expertise in ultracentrifugation, by incorporating features from its top of the line Optima X Series into the Avanti High Performance Centrifuges. The Avanti Series improves workflow by delivering high throughput performance and an expanding and increasingly varied separations capability. This ranges from high efficiency, high volume separations using fixed angle rotors to high force zonal separations with swinging bucket rotors. 

For applications that use common, disposable conical tubes, JA-14.50 rotors extend the applications and flexibility of the company’s Avanti JXN Series. While greater capacity results in higher throughput, the rotors maintain the precision performance offered by products in the Avanti line and are the only high-performance rotors capable of spinning 50, 15, 5 and 1.5 mL conical tubes, and 50, 15 and 10 mL round bottom tubes and bottles at their maximum speeds.

Delivering a top speed of 14,000 rpm and rcf of 35,000 x g, JA-14.50 rotors hold up to 16 x 50 mL conical tubes and maximise the number of 50 mL conical tubes that can be processed in a single run. The fixed-angle rotor is intended for general pelleting of cells, bacteria and food products; separating proteins, viruses and subcellular fractions; running concentrators and columns; and for phase separation and binding studies.

Avanti rotors, including the new JA-14.50 rotor, have a unique ID that is tracked using magnetic sensors. Dynamic Rotor Inertia Check and the ID for Automatic Rotor Identification are used on Avanti Series centrifuges to ensure that no individual rotor exceeds the maximum speed permitted.

Shared Environments
The inclusion of the MobileFuge remote application in both the Avanti JXN and Optima X series centrifuges makes it possible to communicate with a research lab’s central network, further enhancing their suitability for shared lab environments. The application enables scientists to monitor up to 16 instruments from anywhere they have an internet connection and either an Apple iOS or Android device. Currently, Beckman Coulter is the only centrifuge company which offers this level of network connectivity.  

Monitoring multiple instruments becomes easy once Optima XPN and Avanti JXN Series instruments are configured so that they are always connected to the lab’s IT network. Scientists can then access instrument data, so they can carry out remote monitoring and control and error handling via the central network.

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*BioSafety is a term intended to describe the enhanced biocontainment features of our products.

**BioCertified is a term used to describe our products which have been tested and validated to demonstrate containment of microbiological aerosols by an independent, third-party facility (Health Protection Agency, Porton Down, UK or USAMRIID, Ft. Detrick, MD, USA). Improper use or maintenance may affect seal integrity.

Beckman Coulter, the stylized logo, Optima and Avanti are trademarks of Beckman Coulter, Inc. and are registered with the USPTO.