Laboratory Products
From Targeted Regions to Exomes and Genomes
Feb 17 2010
GATC Biotech now offers unique human genome sequencing services using state-of-the-art enrichment technologies from Agilent along with Next-Generation sequencing systems such as Roche GS FLX and Illumina Genome Analyser IIx. Customers can combine any number of samples with any size of targeted region to be subsequently sequenced on any available sequencing technology. The deep sequencing of specific regions on a large number of samples is now affordable and within reach. GATC uses, for example, the SureSelect Targeted Enrichment system and the On-Array DNA Capture system from Agilent.
Sample tagging/barcoding will decrease the sequencing costs. For the transcriptome analysis the new Agilent SureSelect Human All Exon Kit can be used. Complete human genome re-sequencing is also available. The bioinformatic analysis includes mapping, SNP/InDel analysis and visualisation. “We did a re-sequencing project with five human genomes for the DKFZ in Heidelberg as a pilot study and were amazed by the high potential of these applications for cancer research, diagnostics or other fields of clinical research,” said Peter Pohl, CEO of GATC Biotech.
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