New Automated Inhaler Tester Accommodates Any Design

The new Automated Emitted Dose (AED) system introduced by Astech Projects addresses both the demand for in-line high throughout inhaler testing as well as all variations in device design. Used to verify consistent dose delivery, this modular and scalable AED system incorporates sophisticated software for random sample collection, analysis and tracking using bar code technology.

In addition to these key features, Astech's AED system has the ability to revolutionise this field. Traditionally, batch testing has been carried out in isolation, away from the manufacturing environment. However, Astech's AED system could allow for in-line emitted dose testing where results generated from devices picked off the production line would determine whether full batch production should continue. Therefore, providing an alternative, that is both cost and time efficient.

The AED collection chamber ensures accurate sample collection and recovery due to its small internal volume and unique design. The active pharmaceutical ingredient can be recovered using as little as 25ml of solvent, even after rinsing. The AED system also incorporates a fully automated HPLC vial collection module with capacity for up to 400 HPLC vials.

Advanced software allows tight control of the dose actuation parameters including number of doses, device weighing, duration between shots and actuation speed. Dose firing parameters and device performance checks are also controlled in this manner.

The AED system with integrated software has been produced for both R&D development and manufacturing quality control following Good Practice and Compliance for Electronic Records and Signature, Part 2 and is fully compliant with 21 CFR Part 11 and Good Automated Manufacturing Practice (GAMP).

The AED system is just one of a range of high quality automated systems produced by Astech Projects and complements their portfolio of systems for drug delivery testing.