Biotechnology: Two New Functional MBL Elisas

Two new ELISA kits for assaying Human Mannose-Binding Lectin (MBL) are now available from Cambridge Bioscience the Human MBL ELISA Mannan Binding Assay and the Human MBL-C4 Activation Complex ELISA. These kits are the latest in the HyCult Biotechnology range of MBL products. Both assays feature pre-coated microwells for immediate use and have an efficient format (2 plates with 12 disposable 8-well strips) allowing a free choice of batch size for the assay. Protocols are simple and can be performed in less than 4.5 hours.

MBL, a member of the collectins, is an important element in innate immunity and is able to activate the complement activation pathway independent of the classical and alternative pathways. Measurement of functional MBL is of interest in studies on bacterial infections, autoimmune diseases, cancer, HIV, transplantation, atherosclerosis, cystic fibrosis and many other diseases.