• New QDa Detector Brings Push-Button Mass Detection to Chromatography

Chromatography

New QDa Detector Brings Push-Button Mass Detection to Chromatography

Waters Corporation introduces the new Waters® ACQUITY  QDa™ Detector, the first mass detector to bring high-quality, mass spectral data to chromatographic separations. Waters is now shipping the new mass detector worldwide.

Designed as a synergistic component of a chromatographic system, the ACQUITY QDa Detector is compatible with Waters ACQUITY® UltraPerformance LC® (UPLC®), ACQUITY UltraPerformance Convergence Chromatography™ (UPC2®), Alliance® high performance liquid chromatography (HPLC) and Waters supercritical fluid chromatography (SFC) and LC-based purification systems.

The ACQUITY QDa Detector addresses the barriers of complexity, size and cost that have hindered the adoption of mass spectrometry for everyday use. It is purposefully designed for analytical scientists who need mass spectral data without the complexity of a mass spectrometer. With the on/off simplicity that analytical scientists have long wanted from mass spectrometry, the ACQUITY QDa Detector fully automates sample analysis and eliminates sample-specific adjustments for certainty in sample results, from user to user and system to system. Robust and reliable enough for routine use, the ACQUITY QDa Detector generates the high quality mass spectral data expected of a single quadrupole mass spectrometer in a mass detector no bigger than a familiar photodiode array (PDA) detector. 

The ACQUITY QDa Detector complements optical detection, such as the PDA detector, by confirming the identity of compounds with mass spectral information. Additionally, the ACQUITY QDa Detector extends the limits of sample detection for a chromatographic separation by quantifying compounds having no UV response or that are present at levels not detectable and quantifiable by optical detection.  By simplifying laboratory workflows, the detector enhances the value of every analysis and increases productivity by eliminating the need to run additional assays or turn to time-consuming alternative techniques in order to establish with certainty the levels and identity of specific sample compounds.

The ACQUITY QDa Detector is available now for separations systems running Empower® 2 & 3 Chromatography Data System (CDS) software, including enterprise deployment with automated qualification. Empower 3 makes mass and UV spectral data processing as integrated as the separations systems they were acquired on. The ACQUITY QDa Detector is also available now for MassLynx® 4.1 Mass Spectrometry Software.


Digital Edition

Lab Asia Dec 2025

December 2025

Chromatography Articles- Cutting-edge sample preparation tools help laboratories to stay ahead of the curveMass Spectrometry & Spectroscopy Articles- Unlocking the complexity of metabolomics: Pushi...

View all digital editions

Events

Smart Factory Expo 2026

Jan 21 2026 Tokyo, Japan

Nano Tech 2026

Jan 28 2026 Tokyo, Japan

Medical Fair India 2026

Jan 29 2026 New Delhi, India

SLAS 2026

Feb 07 2026 Boston, MA, USA

Asia Pharma Expo/Asia Lab Expo

Feb 12 2026 Dhaka, Bangladesh

View all events