Industry First UPLC-Based SFC Analytical System

The Waters ACQUITY UPSFC System is a holistically designed analytical system combining the advantages of sub-2-μm particle technology and the efficiency of supercritical fluid chromatography (SFC). Built on proven Waters® UltraPerformance LC (UPLC) technology, this new system offers up to 10X shorter run times, reduces solvent usage by as much as 95%, and cuts the cost of analyses by as much as 99% while giving laboratories a greener alternative to normal phase chromatography for chiral and achiral separations.

Waters ACQUITY® UPSFC System enables scientists to conduct normal phase chromatographic separations using carbon dioxide as the primary mobile phase rather than expensive and toxic solvents saving laboratories tens of thousands of dollars over the lifetime of an instrument. The newest member of Waters family of ACQUITY systems, the Waters ACQUITY UPSFC System offers laboratories significant advantages over traditional HPLC for routine UPSFC separations in research or regulated laboratories across many industries.

“In 2004, Waters revolutionised liquid chromatography with the introduction of sub-two micron UPLC separations resulting in significantly better data quality. Today, this proven and reliable technology offers that same potential for analytical supercritical fluid chromatography,” said Harbaksh Sidhu, General Manager, Waters SFC Operations. “As the newest member of Waters family of ACQUITY systems, the ACQUITY UPSFC System provides the same impressive separation, resolution, and speed attributes of UPLC with the outstanding green benefits of SFC.”

Using specially designed Viridis™ Columns the ACQUITY UPSFC System offers the ruggedness and dependability scientists are looking for, with the ease of use they’ve come to expect from liquid chromatography. The system is fully compatible with Waters industry-leading Empower™ and MassLynx™ informatics software and Waters UV and mass detectors.