Peak Scientific Gas Generators for LCMS Applications

Peak Scientific Instruments has a mission to provide a safe, convenient and reliable solution for analytical instruments and analysers that require a source of gas for normal operation.

With more than 10 years of experience as a specialist manufacturer of gas generators, Peak Scientific has become a world leader in the field of generator technology for the GC and LCMS markets, designing, manufacturing & supporting products, which meet and exceed the needs of the analytical instrument industry.

Global Service & Support is provided through an extensive network of field service engineers and technical support specialists from Peak and its authorised distributors in over 70 countries.

Replacing Traditional Gas Supply Sources

Most users will be aware of the dangers associated with combustible gas cylinders but nevertheless accept them because they have been used in laboratories for a very long time. However, traditional supply methods have become inconvenient as the capacity for gas increases with the latest LCMS systems, many consuming up to 1,200 litres of nitrogen per hour at atmospheric pressure during API operation. This is equivalent to the consumption of a large cylinder of nitrogen per day which would be inconvenient for long sample runs or a high throughput laboratory where instrument uptime, cost and convenience are key factors.

High Purity Source of Nitrogen Gas

The gas requirements for LCMS systems are often taken for granted and not appreciated or understood until results are analysed. Only then, it becomes apparent that poor quality nitrogen can be responsible, either for background interference that can reduce the detection capabilities of the system, or in some cases, the introduction of contaminants that can be difficult and costly to remove from the mass spectrometer. With continual improvement in instrument performance, the limits of detection are being pushed even further as scientists strive to realise the potential of the latest LCMS Technology. Quality and consistency of the nitrogen supply will therefore continue to play an important role.

Peak Scientific gas generators offer a constant supply of high purity nitrogen, 24/7, with minimal interruptions to sample analysis or operator involvement. Generation of clean, dry, phthalate free nitrogen from laboratory air involves several discrete processes which separate the components of air into its constituent gases. Peak’s unique design incorporates a hollow fibre membrane, coalescing filters, activated carbon and a dryer membrane to produce nitrogen at the desired purity and flow for LCMS applications.

Immediate Performance and Return On Investment

In a busy laboratory environment with a high sample throughput, a constant supply of gas is crucial to ensure uninterrupted analysis.

Peak Gas Generators are unique in that they are simple to install and easy to use. After initial installation and set up, the generator will operate continuously with virtually no operator involvement and optimum performance can be maintained with an annual service visit. Elimination of the purchasing process, storage and movement of cylinders will also significantly reduce the time and costs associated with supplying nitrogen LC/MS/MS systems.

Peak Scientific Nitrogen Generator Solutions

Working closely with the manufacturers of LC/MS/MS instruments, Peak Scientific has developed an unrivalled reputation for providing quality gas generator products that provide the end user with a consistent, safe & cost
effective supply of gas on-site in the laboratory. This close relationship with the market has enabled us to provide customised solutions to meet the evolving needs of different applications.

For example, Peak Scientific have a long standing relationship with MDS Sciex/ Applied Biosystems to supply a complete range of bespoke nitrogen generators for source, curtain & exhaust gas for all API Systems up to
and including the latest model, the API5500™. Customised solutions for the latest Photospray Application & multiple API installations are also available.

At Waters Corporation, Peak Scientific generators have been scientifically tested and validated to supply nitrogen at the desired flow rate, pressure and purity required for their entire range of LCMS systems. Peak Scientific is the only gas generator manufacturer with a formal worldwide OEM Agreement for the supply of gas generators and services to Waters Corporation.

For several years now, Peak Scientific has been working with Perkin Elmer who supply a complete MS/MS system for newborn screening applications, incorporating a Waters tandem mass spectrometer and Peak Scientific nitrogen generator to provide a total solution in a unique, single package.

In cooperation with ThermoFisher Scientific, Peak Scientific has developed a new, customised nitrogen generator, which delivers a premium solution for the MSQ™ family of mass spectrometers.

A version of this generator is also supplied to the Dionex Corporation along with the MSQ™ mass spectrometer.

As a niche market company, focussed purely on gas generators for laboratory applications, Peak Scientific Instruments can move quickly to provide you with the right solution for your instrument and application.

For enquiries or more information, please contact Peak Scientific (marketing@peakscientific.com).