Chromatography
New Series 2000 Tablet Analyser
May 15 2007
The Series 2000 is a diode array spectrometer with a Sample Transport Module that moves a sample cell in front of a light beam to allow 15 separate scans to be collected for each sample. For measuring coating thickness, the tablets are loaded into a 16 or 28mm thick cell which is then placed into the instruments sample cell holder. A motor and gear wheel drives the cell down and up, stopping in up to 15 separate locations along the 105mm long viewing window. NIR light passes through the cell and the light is transflected, a combination of transmittance and reflectance, through the tablets. NIR light is absorbed by the coating on the tablets. The thicker the coating the more NIR light that is absorbed. The analysis time for measuring coating thickness is less than 2 minutes.
For measuring Tablet Uniformity, a different sample cell is used. The tablets are placed individually into a spacer that holds between 10 and 20 tablets, depending on the size of the tablets. Each tablet is located over a whole in the spacer. When the spacer with loaded tablets is placed into the Squeeze Cell and loaded into the Series 2000 Sample Transport Module, tablets are scanned individually by passing light through each tablet and into the optics. The composition of each tablet is computed and stored in memory. The average results for up to 4 constituents and the standard deviations for all results are shown on the screen. By uploading the results file to a PC, the complete profile of for all tablets can be obtained.
Digital Edition
Lab Asia 31.3 June 2024
June 2024
Chromatography Articles - Enhancing HPLC Field Service with fast-response, non-invasive flowmeters Mass Spectrometry & Spectroscopy Articles - UV-Vis and fluorescence spectroscopy illumina...
View all digital editions
Events
Jun 26 2024 Tokyo, Japan
Jul 03 2024 Gandhinagar, India
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa