Minimising sample loss: The RSA™ advantage in uncoated autosampler vials

In high-precision analytical workflows, even the vial can influence your results. Microsolv’s RSA™ (Reduced Surface Activity) Autosampler Vials are uniquely engineered to eliminate a common source of variability - surface interactions - without relying on coatings. By starting with a cleaner, more inert glass surface, RSA™ vials help ensure your samples stay true from injection to analysis.

Unlike coated vials that rely on surface treatments to reduce reactivity, RSA™ vials are completely uncoated. Instead, they are manufactured using a proprietary process that inherently reduces surface activity in the glass itself. This eliminates the need for coatings, which can degrade over time or introduce unwanted variables into sensitive analyses.

By minimising reactive sites such as silanols, RSA™ vials provide a more stable and inert environment for your samples. This is especially critical when working with low-concentration or adsorption-prone compounds like peptides, proteins, and basic drugs.

Designed for universal compatibility with all major autosamplers, RSA™ vials are a practical upgrade for laboratories aiming to improve reproducibility and reduce variability. Whether you're conducting pharmaceutical, environmental, or clinical research, these uncoated vials offer a dependable solution for high-performance workflows.

Explore how RSA™ vials can help reduce variability and improve your chromatography results:

•    RSA™ vials | screw & snap tops - Microsolv Technology Corporation
•    What is RSA™ Glass? | Autosampler | Chromatography | MicroSolv - MicroSolv Technology Corp
•    Effect of diluent on analyte adsorption to glass autosampler vials - White Paper