TLC to MS – Direct and Rapid

Not all samples may be processed by HPLCMS. In the past unknown substances were then scraped off from the TLC plate, eluted into a tube and transferred in the MS. Now the convenient and universal Camag TLC-MS
Interface is available which semi-automatically extracts zones of interest and directs them online into all common brands of LC-coupled mass spectrometer or extracts them into vials for NMR or (ATR-)FTIR, static nanospray, direct inlet El-MS and MALDI. The interface extracts the complete substance zone with its depth profile and thus allows detections comparable to HPLC down to the pg/zone ranges. The interface has been proven to be one of the most reliable and versatile interfaces for TLC/HPTLC-MS coupling.