Next-generation Horizontal Top-of-the-line Maldi-TOF/TOF Mass Spectrometer for LC-Maldi at Pittcon 2007

At Pittcon 2007, Bruker Daltonics announced the presentation of its next-generation horizontal top-of-the-line ultraflex® III smartbeam? MALDI-TOF/TOF mass spectrometer. The new ultraflex III combines various innovative features and further pushes the TOF/TOF performance envelope for applications like LC-MALDI and MALDI molecular imaging, where scientists require the highest sensitivity and speed.

An even further improved smartbeam laser with computer-controlled settings of the laser focus size from 10 µm to 80 µm makes the new ultraflex III the ideal choice for MALDI molecular imaging. Absorbing tissue areas can now be scanned with a very small laser focus and adjustable repetition rates from 1 Hz to 200 Hz, providing maximum sensitivity.

The ultraflex III boosts sensitivity even further and increases acquisition speed by a factor of three for LC-MALDI workflows, in comparison to the previous ultraflex II system. The all-purpose WARP-LC? workflow software supports intelligent, result-dependent LC-MALDI acquisition, protein sequence validation, PTM screening and accurate quantitative proteomics for all label chemistries, to ensure outstanding top-of-the-line ultraflex III TOF/TOF performance.

"Enhanced sensitivity and speed performance enhancements make the ultraflex III an innovative system which is ideal for virtually all MALDI-TOF/TOF applications. Bruker's unique smartbeam technology, in combination with the new variable focus size, makes the ultraflex III particularly versatile not only for MALDI imaging but for a broad range of large molecule analyses," commented Bruker Daltonics Executive Vice President Dr. Michael Schubert. "Our extensive, fully-integrated MALDI-TOF product portfolio, including our brand-new autoflex III smartbeam and ultraflex III smartbeam TOF/TOF instruments, further establishes Bruker Daltonics' growing leadership position in expression proteomics and clinical proteomics."