Exploring the Feasibility of Employing Supercritical Fluid Chromatography (SFC)-UV-MS for Qualitative and Quantitative Analysis of Fat Soluble Vitamins in Dietary Supplements

Vitamins are biologically active compounds required for an organism’s normal health and growth. While the required dose of vitamins is typically
obtained through a balanced diet, additional vitamins, if necessary, can be obtained through various dietary supplements. The level of vitamins in
food or supplements may be as low as a few micrograms per 100 g. Vitamins are also often accompanied by an excess of compounds with similar
chemical properties. With increased regulation for supplement labelling (Title 21 CFR Part 101), it is therefore important to have robust and sensitive
methods to not only quantify, but also to identify the vitamins in food and supplements.