• Mass Spectrometry Boundaries Expanded

Chromatography

Mass Spectrometry Boundaries Expanded

Waters Corporation recently launched the Waters® SYNAPTTM MS system, a next- generation quadrupole acceleration, time-of-flight (oa-Tof) mass spectrometry (MS) platform. SYNAPT MS is a key part of Waters' strategy to enhance the quality and productivity of life science and drug discovery and development workflows.
Additionally, the SYNAPT MS system is the only platform which provides an upgrade pathway to the SYNAPT High Definition MS(TM) (HDMS(TM))
system, uniquely enabling researchers to analyse samples differentiated by size, shape and charge, as well as mass, ultimately providing new
capabilities that can help them meet and exceed future requirements.
SYNAPT MS is a central component of Waters' system level solutions - combining ACQUITY UltraPerformance LC(R) (UPLC(R)) separations, Exact Mass MSE data acquisition and 'chemically intelligent' MassLynx(TM) Informatics - designed to generate high quality, comprehensive data from
complex biological samples, maximise confidence in results and enable scientists to make better informed decisions. SYNAPT MS Systems also offer unparalleled versatility and flexibility Designed for leading researchers working at the boundaries of conventional mass spectrometry
capabilities who need to further characterise and define their samples, Waters SYNAPT HDMS systems offer unique, enabling functionality. Using
Waters' patented TriWave(TM) technology, SYNAPT HDMS systems combine high-efficiency, ion mobility-based, measurements and separations with
high-performance quadrupole, time-of-flight mass spectrometry. SYNAPT HDMS systems enable researchers to differentiate molecules by size, shape and charge, as well as mass, and to deliver increased
specificity and sample definition beyond that achievable by conventional mass spectrometers.

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Lab Asia Dec 2025

December 2025

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