Conquering Mass Spectrometry Application Challenges

Waters Corporation introduced eight new MassLynx™ workflow enhancements at the 57th American Society of Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Allied Topics, all designed
to enhance laboratory productivity and expand mass spectrometry applications.

Brian Smith, Vice President, Mass Spectrometry Business Operations for the Waters Division, said: “These software innovations realise the full potential of mass spectrometry across our entire portfolio of LC/MS and GC/MS systems. MassLynx software continuously addresses new analytical challenges, and streamlines existing ones, through advanced data interrogation capabilities and simplified workflow processes.”

The POSI±IVE system™ is for high throughput screening of complex food safety, water quality and environmental samples by combining qualitative and quantitative processes into one. POSI±IVE takes Waters system solution paradigm to the next level by uniquely integrating chromatography, exact mass MS and informatics for screening applications. The BiopharmaLynx™ 1.2 increases confidence in peptide characterisation leveraging comprehensive exact mass UPLC/MSE data in biopharmaceutical applications. Quanpedia, QCMonitor and TrendPlot, critical components of the Xevo™ TQ MS quantitative workflow solution software, are now available for a broader range of Waters mass spectrometers. Laboratories will cut sample analysis times and optimise resource utilisation to increase productivity with the latest version of OpenLynx™ Open Access. Clinical pathology laboratories will benefit from automated workflows for UPLC/MS/MS that include seamless HL7 LIMS integration. MetaboLynx™ XS and MarkerLynx™ XS for accelerated metabolite identification and profiling are now available on all Waters MS Systems. Management of large proteomic data sets is accelerated with ProteinLynx Global SERVER™ (PLGS) 2.4 for nanoACQUITY 2D UPLC/MSE while data are now also interchangeable with PRIDE, Scaffold and mzML. DriftScope™ 2.1 features ion mobility spectrometry (IMS) peak detection, visualisation & comparison, together with collision cross section (CCS) determinations, for the original SYNAPT High Definition MS™ system and the new SYNAPT G2 HDMS system.