Chromatography
Rapid Removal of Phospholipids Gives Scientists a New Tool to Advance Drug Discovery and Development Efforts
Oct 06 2010
Waters new Ostro™ Sample Preparation Plate, representing a novel approach for the removal of phospholipids from biological samples is now available. When compared to other phospholipid removal devices and traditional liquid-liquid extraction (LLE) methods, Ostro removes up to 30 times more phospholipids.
Phospholipids have been cited as a major cause of matrix effects in the LC/MS analysis of biological samples. Ostro, with its proprietary, patent-pending design, was specifically created to overcome this hurdle by offering a “best-in-class” solution that removes multiple families of phospholipids.
The Ostro 96-well plate format utilizes in-well protein precipitation with a single, rapid, pass-through method that provides a quick, reliable, and reproducible solution.
“We are excited and proud to introduce Ostro as an extension of our comprehensive family of 96-well sample preparation plates”, comments Dr. Diane Diehl, Director, Sample Preparation, Waters Division. “Ostro will be a valuable tool for researchers who are struggling with phospholipid interferences, and provide a complimentary solution to Oasis® SPE products - Waters premier solid-phase extraction solution.”
For more information on Waters® Ostro Sample Preparation Products:
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