Chromatography
Detecting Nitrosamine content in Pharmaceutical Drugs
Mar 10 2020
The news has recently been full of worldwide high-profile product recalls of various pharmaceutical drugs that have been found to contain nitrosamines. Nitrosamine are carcinogenic compounds so need to be monitored to ensure unsafe levels are not found in consumer products.
The Ellutia 800 Series TEA is the industry standard for nitrosamine detection thanks to is selectivity and sensitivity for Nitroso compounds. For testing of pharmaceutical drugs, The 800 Series TEA can be interfaced to a chemical stripping system that allows for rapid testing of ATNC (Apparent Total N-nitrosamine content). This quickly gives an accurate result for the total nitrosamine content of a sample showing both volatile and non-volatile components.
Any positive sample can then be further analysed by an 800 Series TEA interfaced to a GC where volatile nitrosamines such as NDMA (N-Nitrosodimethylamine) can be separated and quantified.
For further information on how the Ellutia 800 Series TEA can help with the detection of nitrosamines in pharmaceutical drugs please visit
Digital Edition
International Labmate Buyers' Guide 2024/25
June 2024
Buyers' Guide featuring: Product Listings & Manufacturers Directory Chromatography Articles - Enhancing HPLC Field Service with fast-response, non-invasive flowmeters - Digital transformatio...
View all digital editions
Events
Jul 03 2024 Gandhinagar, India
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa
Jul 28 2024 San Diego, CA USA