• Shimadzu – Nexera QX Multiplex System

Labmate Awards for Excellence 2025

Shimadzu – Nexera QX Multiplex System


Best separation science innovation


Nexera QX Multiplex System maximize mass spectrometer productivity. Multiplex uses multiple, alternating sample introduction streams to keep the mass spectrometer working continuously. QX maximizes laboratory profitability by keeping your capital investment working. In conventional LCMS analysis, the system cycle time includes steps in addition to MS data acquisition. Column flushing, equilibration, and autosampler rinsing add to the time between runs, consuming valuable mass spectrometer time. QX significantly increases your laboratory throughput and profitability.

The QX System adds multiple injection valves to the Nexera SIL-40 series autosampler, the industry standard for fast and clean injections. It also intelligently controls dedicated Nexera UHPLC pumps to automate flow line rinsing of each analytical stream to mitigate carryover from extreme samples. 

QX Solution software is a single vendor, integrated solution over all of the hardware, from sample introduction streams to error handling—a single point of control. QX is also specifically designed for the high-throughput laboratory, allowing for the easy import of spreadsheet sample batches. QX Solution simplifies valve control, gradient control, and injection timing. QX Solution features stream-dedicated status monitoring. Smart management of analysis streams and submitted samples is built-in. If one stream goes down, QX will run the sample on any available streams.
Equipped with Ultra Fast Mass Spectrometry (UFMS) technology, Shimadzu triple LC-MS systems are tailored solutions for the Nexera QX, providing high performance and excellence in data quality. Ultra-fast data acquisition speeds enable optimum throughput, allowing sensitive quantitative analyses with exceptional robustness and ease of use.

Our most powerful tandem mass spectrometer, the LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation through reduced matrix effects and less contamination inside the instrument, resulting in maximized uptime, the utmost in data quality, and a more efficient analytical workflow.


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