Mass Spectrometry & Spectroscopy
Using Benchtop NMR in drug development laboratories
Jan 04 2024
Are you interested in gaining a greater understanding of your candidate molecules or reaction intermediates?
NMR spectroscopy is one of the most powerful tools for the structural elucidation of an unknown chemical compound, and the structural confirmation of known compounds. During the later stages of the drug development and manufacturing processes benchtop NMR, can be used to investigate a range of samples from quality control of stock chemicals, to identifying components in complex reaction mixtures.
In this application note, the X-Pulse broadband benchtop NMR Spectrometer from Oxford Instruments is used to perform a full structural elucidation of the anti-inflammatory drug, ibuprofen. It explains how using one- and two-dimensional proton and carbon-13 spectra, the molecule is identified as the monocarboxylic acid, ibuprofen.
Read the application note: Structural Elucidation by Benchtop NMR Spectroscopy: Ibuprofen.
Digital Edition
International Labmate Buyers' Guide 2024/25
June 2024
Buyers' Guide featuring: Product Listings & Manufacturers Directory Chromatography Articles - Enhancing HPLC Field Service with fast-response, non-invasive flowmeters - Digital transformatio...
View all digital editions
Events
Jul 07 2024 Dublin, Ireland
Jul 20 2024 Denver, CO, USA
Jul 21 2024 Cape Town, South Africa
Jul 28 2024 San Diego, CA USA
Jul 30 2024 Jakarta, Indonesia