New EVOLUTE® CX for Improved Sample Preparation

Biotage announced the introduction of the new EVOLUTE® CX sample preparation range. EVOLUTE CX is a mixed-mode resin-based SPE sorbent for the extraction of basic drugs from biological fluids using a generic procedure, minimising method development time for bioanalysts. EVOLUTE CX removes protein, phospholipids, and salt interferences,
delivering cleaner extracts with high reproducibility for accurate quantitation and trouble-free analyses through preclinical and clinical trials.
Biotage’s EVOLUTE CX uses a combination of robust polymer chemistry, uniform coverage of sulfonic acid (SO3-) groups and optimum exchange capacity to provide greater than 85% recovery on a broad range of sample matrices. The surface characteristics of every batch are tested to ensure consistency. A combination of optimised pore size, sorbent
chemistry and associated generic method results in extremely clean extracts for LC–MS/MS. The Biotage EVOLUTE family of products now includes EVOLUTE ABN (30ìm and 50ìm) and EVOLUTE CX. EVOLUTE products provide highly effective solutions to the problems of ion suppression and matrix effects from dirty extracts. These high performance products allow scientists to use a generic approach for a wide range of compounds, reducing method development time while improving extract cleanliness.