Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications
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Sophie Bekisz is a Ph.D. student at the University of Liège, graduated as Biomedical Engineer in 2018. She is a FRIA grantee of the Fonds de la Recherche Scientifique – FNRS. Her research focus is on the modelling of the process of lymphangiogenesis with mathematical and computational tools. Classical biomedical approaches using in vitro and in vivo models are combined with engineering approaches using in silico (computer) models. This multidisciplinary character enables to better understand the fundamental mechanisms regulating lymphangiogenesis.
Liesbet Geris is Collen-Francqui Research Professor in Biomechanics and Computational Tissue Engineering at the university of Liège and KU Leuven in Belgium. Her research focusses on the multi-scale and multi-physics modeling of biological processes. Together with her team and their clinical and industrial collaborators, she uses these models to investigate the etiology of non-healing fractures, to design in silico potential cell-based treatment strategies and to optimize manufacturing processes of these tissue engineering constructs. Liesbet is scientific coordinator of the Prometheus platform for Skeletal Tissue Engineering (50+ researchers). She has edited several books on computational modeling and tissue engineering. She has received 2 prestigious ERC grants (starting in 2011 and consolidator in 2017) to finance her research and has received a number of young investigator and research awards from the in silico and regenerative medicine communities. She is a former member and chair of the Young Academy of Belgium (Flanders) and member of the strategic alliance committee of the Tissue Engineering and Regenerative Medicine Society. She is the current executive director of the Virtual Physiological Human Institute and in that capacity she advocates the use of in silico modeling in healthcare through liaising with the clinical community, the European Commission and Parliament, regulatory agencies (EMA, FDA) and various other stakeholders. Besides her research work, she is often invited to give public lectures on the challenges of interdisciplinary in research, women in academia and digital healthcare.