The VANTAstar® is the latest addition to our family. This compact multi-mode microplate reader was conceived for ease-of-use and flexibility and ensures effortless detection setup for a simplified data generation. Equipped with our patented dual LVF Monochromators™ system, filters, UV/vis spectrometer, and Enhanced Dynamic Range technology, it can cover a wide range of applications in basic research and life science.
The VANTAstar is an upgradable multi-mode microplate reader compatible with all plate formats up to 384 wells. The Enhanced Dynamic Range (EDR) technology, a fast full-plate auto-focus, and luminescence cross-talk reduction make assay detection easier than ever and manual optimization superfluous.
With its Atmospheric Control Unit for gas control, temperature incubation, multiple shaking options, well scan and reagent injectors with heater and stirrer, the VANTAstar supports all live cell-based assays. The VANTAstar is also available with only filter-based detection. Check here more details about the VANTAstar F.
The VANTAstar comes now with Voyager, BMG LABTECH´s new microplate reader control interface. Designed to remove complexity while maximising flexibility, Voyager makes data acquisition more intuitive than ever.
You are planning to inject living cells with a microplate reader? Read here how the VANTAstar with magnetic stirrer and heater keeps your cells happy and in suspension till the moment of injection.
Intramolecular bivalent glues can be used for the targeted degradation of proteins. Find out how their binding behaviour can be investigated using microplate readers.
Antibiotic resistance continues to increase. Find out here how BOCILLIN can be used to study resistant penicillin binding protein variants using fluorescence polarization.
The threat of growing antibiotic resistance is constantly increasing. Find out here how venom fractions are emerging as a beacon of hope in the search for novel antibiotics.
Have you heard of dTAG degraders yet? Check out this novel approach in targeted protein degradation and learn how it can be used to identify disease-relevant proteins.
Looking for a method to study intracellular bacterial cytotoxicity? This AppNote presents a novel method based on the monitoring of propidium iodide uptake with the CLARIOstar Plus.
Mishra, V;Deshmukh, A;Rathore, I;Chakraborty, S;Patankar, S;Gustchina, A;Wlodawer, A;Yada, RY;Bhaumik, P; 2024
Current research in structural biology 7 100128
Ciccone, L;Camodeca, C;Tonali, N;Barlettani, L;Rossello, A;Fruchart Gaillard, C;Kaffy, J;Petrarolo, G;La Motta, C;Nencetti, S;Orlandini, E; 2023
Pharmaceutics 15(10)
Pang, C;Zhang, T;Chen, Y;Yan, B;Chen, C;Zhang, Z;Wang, C; 2023
Functional & integrative genomics 23(3) 260
Ning, K;Gao, R; 2023
Experimental and Therapeutic Medicine 25(4) 151
Fluorescence intensity (incl. FRET)
Fluorescence polarization
Luminescence (flash and glow) - incl. BRET
Time-resolved fluorescence
TR-FRET
UV/vis absorbance spectra
Top and bottom reading
Endpoint and kinetic
Sequential multi-excitation
Sequential multi-emission
Spectral scanning (fluorescence, luminescence, absorbance)
Ratiometric measurements
Well scanning
6- to 384-well plates, user-definable
LVis Plate with 16 low volume microspots (2 μL)
Robot compatible
High energy xenon flash lamp
Low-noise photomultiplier tube
CCD spectrometer
Dual Linear Variable Filter (LVF) Monochromators™
Linear Variable Dichroic Mirror
Separates ex & em LVF Monochromators
Optical filters:
Ex and em slides hold up to 5 filters each
LVF Monochromators + optical filters
Use one for ex and the other for em
UV/Vis absorbance spectrometer: Full spectra or 8 distinct wavelengths in < 1 sec/well
Filters
FI, LUM, TRF, FP, TR-FRET: 240 - 740 nm
LVF Monochromators™
FI, LUM: 320 - 740 nm
Linear Variable Dichroic
340 - 740 nm
Spectrometer
ABS: 220 - 1000 nm; wavelength precision: ≤ 0.5 nm
FI filters
(top)
< 0.5 pM (< 10 amol/well FITC, 384sv, 20 μL).
FI filters
(bottom)
< 2.5 pM (< 125 amol/well FITC, 384g, 50 μL).
FI monochromator
(top)
< 0.8 pM (< 16 amol/well FITC, 384sv, 20 μL).
FI monochromator
(bottom)
< 3.5 pM (< 175 amol/well FITC, 384g, 50 μL).
Dynamic Range: 8 decades in a single measurement.
FP
< 1.2 mP SD at 1 nM FITC (384sv, 20 μL).
HTRF®
(black and white microplates)
Reader Control Kit (Eu) after 18h (384sv, 20 μL).
Delta F > 700% (High Calibrator).
Delta F > 25% (Low Calibrator).
TRF
< 30 fM europium (< 2.4 amol/well, 384, 80 μL).
LUM
< 0.8 pM (< 15 amol/well ATP, 384sv, 20 μL).
Dynamic range: 8 decades in a single measurement.
ABS with spectrometer
Selectable spectral resolution: 1, 2, 5, and 10 nm.
OD range: 0 to 4 OD; photometric resolution: 0.001 OD.
Accuracy: < 1% at 2 OD.
Precision: < 0.5% at 1 OD and < 0.8% at 2 OD.
Linearity: ≤ 0.8% at 2.0 OD.
Flying mode (1 flash)
9 sec (96), 16 sec (384)
Linear, circular and double-circular with user-definable time and speed
+4 °C above ambient up to 45 °C or 60 °C
Minimum condensation concept: the upper heating plate of the incubation chamber operates at +0.5 °C than the lower plate, heated optic system
Multi-user reader control (SMART Control and Voyager) and data analysis software (MARS).
FDA 21 CFR Part 11 compliance available with SMART Control and MARS.
Integrated fluorophore library.
Width: 35 cm, depth: 52 cm, height: 36 cm; weight: 27 kg
Excitation and emission slides for up to 4 filters each for monochoromator units (VANTAstar), and for up to 5 filters each for filter-only units (VANTAstar F)
Top and bottom: free-air optical light path guided by motor-driven mirrors and dichroics
Automatic focal height adjustment (0.1 mm resolution)
Up to 2 reagent injectors
Individual injection volumes for each well: 3 to 500 μL (optionally up to 1 mL)
Variable injection speed up to 420 μL/s
Reagent back flushing
Heater and stirrer plate
Dimensions: width: 13 cm, depth: 31 cm, height: 26 cm; weight: 6 kg
Sample capacity: sixteen separate microdrop wells for 2 µL samples; one standard cuvette position for up to 1 mL samples
Quality Control Internal Standards (optional): four NIST traceable optical density filters (approximate values of 0.1, 0.3, 0.6 and 1.0 OD); one holmium oxide filter for wavelength accuracy
Dimensions: conforms to SBS standards for microplates
Microplate incubator and shaker
Actively regulates O2 and CO2 - 1-20%
Excitation and emission filters
Upgrades to include options such as additional detection modes, reagent injectors, extended temperature control, etc. are available
Please contact your local representative for more information
LOD = 3 x SD (20 blanks) / slope (6 pt std curve)
96 = 96-well microplates
384sv = 384-well small volume microplates
384g = 384-well glass bottom microplates
Intelligent microplate incubation
Low-volume measurements
Filters for a wide range of applications
Functional Microplate Reader Validation
Enhanced cell-based assays
Fluorescence intensity (incl. FRET)
Fluorescence polarization
Luminescence (flash and glow) - incl. BRET
Time-resolved fluorescence
TR-FRET
UV/vis absorbance spectra
Top and bottom reading
Endpoint and kinetic
Sequential multi-excitation
Sequential multi-emission
Spectral scanning (fluorescence, luminescence, absorbance)
Ratiometric measurements
Well scanning
6- to 384-well plates, user-definable
LVis Plate with 16 low volume microspots (2 μL)
Robot compatible
High energy xenon flash lamp
Low-noise photomultiplier tube
CCD spectrometer
Dual Linear Variable Filter (LVF) Monochromators™
Linear Variable Dichroic Mirror
Separates ex & em LVF Monochromators
Optical filters:
Ex and em slides hold up to 5 filters each
LVF Monochromators + optical filters
Use one for ex and the other for em
UV/Vis absorbance spectrometer: Full spectra or 8 distinct wavelengths in < 1 sec/well
Filters
FI, LUM, TRF, FP, TR-FRET: 240 - 740 nm
LVF Monochromators™
FI, LUM: 320 - 740 nm
Linear Variable Dichroic
340 - 740 nm
Spectrometer
ABS: 220 - 1000 nm; wavelength precision: ≤ 0.5 nm
FI filters
(top)
< 0.5 pM (< 10 amol/well FITC, 384sv, 20 μL).
FI filters
(bottom)
< 2.5 pM (< 125 amol/well FITC, 384g, 50 μL).
FI monochromator
(top)
< 0.8 pM (< 16 amol/well FITC, 384sv, 20 μL).
FI monochromator
(bottom)
< 3.5 pM (< 175 amol/well FITC, 384g, 50 μL).
Dynamic Range: 8 decades in a single measurement.
FP
< 1.2 mP SD at 1 nM FITC (384sv, 20 μL).
HTRF®
(black and white microplates)
Reader Control Kit (Eu) after 18h (384sv, 20 μL).
Delta F > 700% (High Calibrator).
Delta F > 25% (Low Calibrator).
TRF
< 30 fM europium (< 2.4 amol/well, 384, 80 μL).
LUM
< 0.8 pM (< 15 amol/well ATP, 384sv, 20 μL).
Dynamic range: 8 decades in a single measurement.
ABS with spectrometer
Selectable spectral resolution: 1, 2, 5, and 10 nm.
OD range: 0 to 4 OD; photometric resolution: 0.001 OD.
Accuracy: < 1% at 2 OD.
Precision: < 0.5% at 1 OD and < 0.8% at 2 OD.
Linearity: ≤ 0.8% at 2.0 OD.
Flying mode (1 flash)
9 sec (96), 16 sec (384)
Linear, circular and double-circular with user-definable time and speed
+4 °C above ambient up to 45 °C or 60 °C
Minimum condensation concept: the upper heating plate of the incubation chamber operates at +0.5 °C than the lower plate, heated optic system
Multi-user reader control (SMART Control and Voyager) and data analysis software (MARS).
FDA 21 CFR Part 11 compliance available with SMART Control and MARS.
Integrated fluorophore library.
Width: 35 cm, depth: 52 cm, height: 36 cm; weight: 27 kg
Excitation and emission slides for up to 4 filters each for monochoromator units (VANTAstar), and for up to 5 filters each for filter-only units (VANTAstar F)
Top and bottom: free-air optical light path guided by motor-driven mirrors and dichroics
Automatic focal height adjustment (0.1 mm resolution)
Up to 2 reagent injectors
Individual injection volumes for each well: 3 to 500 μL (optionally up to 1 mL)
Variable injection speed up to 420 μL/s
Reagent back flushing
Heater and stirrer plate
Dimensions: width: 13 cm, depth: 31 cm, height: 26 cm; weight: 6 kg
Sample capacity: sixteen separate microdrop wells for 2 µL samples; one standard cuvette position for up to 1 mL samples
Quality Control Internal Standards (optional): four NIST traceable optical density filters (approximate values of 0.1, 0.3, 0.6 and 1.0 OD); one holmium oxide filter for wavelength accuracy
Dimensions: conforms to SBS standards for microplates
Microplate incubator and shaker
Actively regulates O2 and CO2 - 1-20%
Excitation and emission filters
Upgrades to include options such as additional detection modes, reagent injectors, extended temperature control, etc. are available
Please contact your local representative for more information
LOD = 3 x SD (20 blanks) / slope (6 pt std curve)
96 = 96-well microplates
384sv = 384-well small volume microplates
384g = 384-well glass bottom microplates
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