In QC and food testing laboratories a single method approach and high throughput are valuable factors in order to streamline the lab workflow. The ETHOS X method is not matrix dependent, therefore, it uses a single method and setup for virtually any sample and total fat contents. The use of the powerful stirring and closed vessel microwave technology enables the simultaneous hydrolysis and extraction. The ETHOS X processes 15 samples at the time in 3 hours, leading to 45 samples in a single working day with one rotor and up to 75 samples with two rotors. The easyCONTROL software includes a wizard process to assist the operator along the entire process and to collect the process information on every samples in a single platform.