CV Lattes
ORCID
| 2 / 2 | Ongoing grants |
| 23 / 16 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 36 / 18 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 66 / 40 | All research grants and scholarships |
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Associate Professor and head of the Laboratory of Clinical immunology and Allergy (LIM-60), Division of Clinical Immunology and Allergy, Department of Medicine, and Investigator of the Heart Institute/Fundação Zerbini, University of São Paulo School of Medicine (FMUSP). Investigator class 1B, CNPq (Brazilian National Research Council). Coordinator of the Graduate Program of Allergy and Immunopathology at FMUSP. Investigator of the INCT for Investigation in Immunology.MD degree, University of Brasília (1988) and PhD on Immunology, University of São Paulo (1994). Visiting researcher in Stanford University (USA, 1991), Harvard University (USA, 2002), Istituto Roche Milano Ricerche, Italy (1996) and Aix-Marseille Université/INSERM, France ( 2012, 2017). He has experience in translational research on cellular and molecular immunology and immunopathology of human disease, focussing on the following subjects:Chagas disease, chronic Chagas disease cardiomyopathy, vaccine discovery, HIV, COVID-19. Recent emphasis has been on the role of mitochondrial damage, inflammation and genetics, as well as novel treatments for Chagas disease, and identification of biomarkers and vaccine development for COVID-19. In March 2024 he had 194 ublications in peer-reviewed, indexed journals. The publications had been cited 5907 times, with an h index of 45 (ISI/WoS). One patent on an HIV vaccine was granted by USPTO and EPO (US and European Community) and pending in INPI (Brazil). Awarded with the Roche (1994), Santista-Juventude (1998) e Jairo Ramos (2002) nationwide scientific awards. (Source: Lattes Curriculum)
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Research grants
- Genetics and pathogenesis of Chagas Disease megaoesophagus: identification rare pathogenic variants and investigation of their functional impact, AP.R
- Genetic and molecular landscape in Chagas Disease cardiomyopathy: therapeutic and prognostic targets, AV.EXT
- Molecular pathogenesis and genetics in Chagas Disease cardiomyopathy: therapeutic and prognostic targets, AV.EXT
(Only some records are available in English at this moment)
Scholarships in Brazil
- Functional characterization of rare variants in the mitochondrial and inflammatory genes identified in CCC cases using CRISPR-Cas9 engineered AC-16 cardiomyocytes and THP1 monocyte-like cells, BP.PD
- Drug repositioning to identify drugs that ameliorate cytokine-induced mitochondrial dysfunction in cardiomyocytes: Validation of hits found after screening of drug library, BP.DR
- Neutralizing antibodies against different SARS-CoV-2 variants of concern in convalescent and immunized individuals with different COVID-19 vaccines, BP.DR
- Identification of gene polymorphisms and assessment of their prognostic value for arrhythmic forms and SCD in Chagas, BP.TT
- Functional characterization of rare variants in the mitochondrial and inflammatory genes identified in CCC cases using CRISPR-Cas9 engineered AC-16 cardiomyocytes and THP1 monocyte-like cells, BP.PD
- Functional characterization of rare variants in the mitochondrial and inflammatory genes identified in CCC cases using induced pluripotent cell- derived cardiomyocytes(iPSC-CM)., BP.PD
(Only some records are available in English at this moment)
Scholarships abroad
Total / Available in English
EPÍTOPOS, COMBINAÇÃO DE EPÍTOPOS, USOS DE EPÍTOPOS OU SUA COMBINAÇÃO, COMPOSIÇÃO, USOS DA COMPOSIÇÃO, VACINAS PROFILÁTICAS ANTI-HIV-1, VACINAS TERAPÊUTICAS, MÉTODO PARA A IDENTIFICAÇÃO DE EPÍTOPOS E MÉTODOS PARA O TRATAMENTO OU PREVENÇÃO PI0504117-1 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto ; Jorge Elias Kalil Filho ; Simone Gonçalves da Fonseca - September 2005, 05
EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION US12/073,401 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto ; Jorge Elias Kalil Filho ; Simone Gonçalves da Fonseca - March 2008, 05
EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION EP20060775031 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto ; Jorge Elias Kalil Filho ; Simone Gonçalves da Fonseca - April 2006, 09
EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION PCT/BR2006/000175 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto ; Jorge Elias Kalil Filho ; Simone Gonçalves da Fonseca - April 2006, 09
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