Ancient genomic linkage regulates red blood cell development
A collaboration between the Drakesmith and Higgs Groups at the MRC WIMM has identified an ancient connection between metabolic and transcriptional control of erythropoiesis.
Read moreMRC Translational Immune Discovery Unit
Pioneering the future in the study of human immunity to uncover the molecular pathways driving immune-mediated diseases.
MRC Molecular Haematology Unit
Understanding how mature blood cells are normally made from stem cells and how this is perturbed in common blood disorders.
Centre for Computational Biology
Using computational biology to help understand complex biological systems and combat a range of human diseases.
Latest publications
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DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition.
Ayyadevara VSSA. et al, (2025), Leukemia
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BCL11B-related disease: a single phenotypic entity?
Vedovato-dos-Santos JH. et al, (2025), European Journal of Human Genetics
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Magrolimab plus azacitidine vs physician's choice for untreated TP53-mutated acute myeloid leukemia: the ENHANCE-2 study.
Zeidner JF. et al, (2025), Blood
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3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline.
Yang X. et al, (2025), Adv Healthc Mater
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Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers.
Goncalves T. et al, (2025), Nucleic Acids Res, 53
Upcoming Seminars
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Thursday, 17 April 2025, 12pm to 1pm
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Thursday, 01 May 2025, 12pm to 1pm
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Thursday, 08 May 2025, 12pm to 1pm
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Friday, 09 May 2025, 9.15am to 10.15am
Speakers: Dr Abhinandan Devaprasad