Automated cryo-plasma-FIB for throughput and connectivity for the cryo-electron tomography workflow

Cryo-electron tomography (cryo-ET) provides unprecedented insights into the inner workings of cells, but clear, reliable results depend on high-quality cryo-lamella preparation. The Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (cryo-PFIB) is specifically designed for automated, high-throughput production of cryo-lamellae from vitrified cells. Its Autoloader system provides a unique, direct connection between cryo-FIB-SEM sample preparation and cryo-transmission electron microscopy (cryo-TEM) within the tomography workflow.

Arctis Cryo-Plasma FIB capabilities

High quality lamella preparation

The Arctis Cryo-Plasma-FIB automates high-throughput TEM lamellae production and features Autoloader connectivity for the cryo-electron tomography workflow.

Connectivity for the cryo-ET workflow

With the Autoloader system, the Arctis Cryo-PFIB offers robotic sample loading, automatic sample processing, and storage of up to twelve frozen specimens with direct connection to any Autoloader-equipped cryo-TEM.

Arctis Cryo-Plasma-FIB resource

Learn more from scientists who are using the Arctis Cryo-PFIB and take a closer look with on-demand webinars and videos.

Correlation to light microscopy

“On-board” integrated fluorescence light microscope (iFLM) allows the same area to be observed with light, ion, or electron beams.

Cryo-ET service and support

To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and workflow validation.

Explore cryo-electron tomography

The Thermo Scientific cryo-electron tomography (cryo-ET) workflow is a complete end-to-end workflow covering cell culture to flash freezing cells to final 3D visualization and analysis.

For Research Use Only. Not for use in diagnostic procedures.

1x1 image pixel for data collection